Bidirectional Transport: Matchmaking for Motors
نویسنده
چکیده
In bidirectional transport, opposing motors frequently require each other for full activity. A new study suggests that mechanical coupling between motors is the key to this reciprocal activation.
منابع مشابه
Traffic by small teams of molecular motors
Molecular motors transport various cargos along cytoskeletal filaments, analogous to trucks on roads. In contrast to vehicles, however, molecular motors do not work alone but in small teams. We describe a simple model for the transport of a cargo by one team of motors and by two teams of motors, which walk into opposite directions. The cooperation of one team of motors generates long-range tran...
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Intracellular transport along cytoskeletal filaments is often mediated by two teams of molecular motors that pull on the same cargo and move in opposite directions along the filaments. We have recently shown theoretically that this bidirectional transport can be understood as a stochastic tug-of-war between the two motor teams. Here, we further develop our theory to investigate the experimental...
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ورودعنوان ژورنال:
- Current Biology
دوره 20 شماره
صفحات -
تاریخ انتشار 2010